反应详情

10 mg (0.037 mmol) of 5-amino-3-methyl-1-(2-octyl)-1H-pyrazole-4-carboxamide and 30 mg (0.129 mmol) of methyl 3,4-methylenedioxyphenylacetate are refluxed for 6 hours in 0.3 ml of a 0.5M ethanolic potassium tert-butoxide solution. After dichloromethane and saturated aqueous sodium hydrogen carbonate solution have been added, the phases are separated. Purification by chromatography gives 2 mg (16%) of a solid, Rf=0.67 (dichloromethane/methanol=15:1).

1. customthe phases are separated
2. customPurification by chromatography