1-(Pyridin-2-ylmethyl)-1H-indazol-5-amine → N6,N6-Dimethyl-N4-(1-pyridin-2-ylmethyl-1H-indazol-5-yl)-pyrido[3,4-d]pyrimidine-4,6diamine Hydrochloride

Participants

Role	Name	HCID	Charge
Reactant	1-(Pyridin-2-ylmethyl)-1H-indazol-5-amine	HCID 21952366	—
Reactant	4-Chloro-6-(N,N-dimethylamino)-pyrido[3,4-d]pyrimidine	HCID 22727453	—
Product	N6,N6-Dimethyl-N4-(1-pyridin-2-ylmethyl-1H-indazol-5-yl)-pyrido[3,4-d]pyrimidine-4,6diamine Hydrochloride	HCID 22727464	—

Reaction Steps

Prepared according to Procedure A from 1-(2-Pyridylmethyl)indazol-5-ylamine and 4-chloro-6-(N,N-dimethylamino)-pyrido[3,4-d]pyrimidine; δH[2H6]DMSO 11.75(1H,s), 9.92(1H,s), 8.62(1H,s), 8.55(1H,d), 8.24(1H,s), 8.14(1H,s), 7.75(4H,m), 7.33(1H,m), 7.08(1H,d), 5.82(2H,s), 3.20(6H,s); m/z (M+1+) 397.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06174889B1
Source dataset	uspto-grants-2001_01
ORD ID	ord-0f9473da1bfa40c0b03277230ae92ebe
Source note	uspto-grants-2001_01