[6-[[(2-Piperidinoethyl)amino]carbonyl]-3-cyclohexenyl]methyl N-octadecylcarbamate → [6-[[(2-Piperidinoethyl)amino]carbonyl]-3-cyclohexenyl]methyl N-octadecylcarbamate hydrochloride

Participants

Reaction Steps

4N Hydrochloric acid/ethyl acetate solution (1.30 ml) was added to a solution of [6-[[(2-piperidinoethyl)amino]carbonyl]-3-cyclohexenyl]methyl N-octadecylcarbamate (2.431 g) in ethyl acetate (50 ml). After being stirred for 30 minutes at room temperature, the reaction mixture was concentrated. The residue was recrystallized with methanol-isopropyl ether mixed solution, thereby yielding the entitled compound (2.407 g) as white solid.

Provenance & Evidence