HCID 21266142, compound → HCID 21266141, compound

HRID 566429Notes

Reaction equation

HRID 566429 reaction equation
[ClH:1].C(OCC)(=O)C.[N:8]1([CH2:14][CH2:15][NH:16][C:17](=[O:43])[O:18][CH2:19][CH:20]2[CH:25]([C:26]([NH:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40])=[O:27])[CH2:24][C:23]([CH3:41])=[C:22]([CH3:42])[CH2:21]2)[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1>C(OCC)(=O)C>[ClH:1].[N:8]1([CH2:14][CH2:15][NH:16][C:17](=[O:43])[O:18][CH2:19][CH:20]2[CH:25]([C:26]([NH:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40])=[O:27])[CH2:24][C:23]([CH3:41])=[C:22]([CH3:42])[CH2:21]2)[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1

Participants

4

Reactant 2

HCID 21266142HCID 21266142, compoundHCID 21866389Hydrogen chloride-ethyl acetate

Product 1

HCID 21266141HCID 21266141, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

4N Hydrochloric acid/ethyl acetate solution (0.51 ml) was added to a solution of {6-[(dodecylamino)carbonyl]-3,4-dimethyl-3-cyclohexenyl}methyl N-(2-piperidinoethyl)carbamate (0.850 g) in ethyl acetate (9 ml) and then stirred for 30 minutes at room temperature. The reaction mixture was concentrated, thereby yielding the entitled compound (0.870 g) as white solid.

Workup

  1. concentrationThe reaction mixture was concentrated

Sources & evidence

ORD record
ord-f0c531a8a51e412a8ec1b3f5fd52dfbc
Source dataset
uspto-grants-2001_01
Patent number
US06174885B1

Reaction notes

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