Potassium Carbonate → N-octadecyl-[6-(trityloxymethyl)-3-cyclohexenyl]formamide

HRID 566430Notes

Reaction equation

HRID 566430 reaction equation
[OH:1][CH2:2][CH:3]1[CH:8]([N:9]([CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[CH:10]=[O:11])[CH2:7][CH:6]=[CH:5][CH2:4]1.[C:30](Br)([C:43]1[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=1)([C:37]1[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1)[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1.C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[CH2:12]([N:9]([CH:8]1[CH:3]([CH2:2][O:1][C:30]([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)([C:43]2[CH:44]=[CH:45][CH:46]=[CH:47][CH:48]=2)[C:37]2[CH:38]=[CH:39][CH:40]=[CH:41][CH:42]=2)[CH2:4][CH:5]=[CH:6][CH2:7]1)[CH:10]=[O:11])[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 11692BromotriphenylmethaneHCID 86756229[6-(Hydroxymethyl)-3-cyclohexenyl]-N-octadecylformamide

Product 1

HCID 86756230N-octadecyl-[6-(trityloxymethyl)-3-cyclohexenyl]formamide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

[6-(Hydroxymethyl)-3-cyclohexenyl]-N-octadecylformamide obtained in Example 1 (2) is reacted with trityl bromide in acetone in the presence of potassium carbonate to obtain N-octadecyl-[6-(trityloxymethyl)-3-cyclohexenyl]formamide.

Sources & evidence

ORD record
ord-54e80bcf171e4e0f9bdbd469da87bec0
Source dataset
uspto-grants-2001_01
Patent number
US06174885B1

Reaction notes

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