1,2-Dichloroethane → HCID 131716892, compound

HRID 566518Notes

Reaction equation

HRID 566518 reaction equation
[CH2:1]([Cl:4])[CH2:2][Cl:3].[CH3:5][O:6][C:7](=[O:15])[C@H:8]([CH2:10][CH2:11][CH2:12][CH2:13][NH2:14])[NH2:9]>O>[CH2:1]([Cl:4])[CH2:2][Cl:3].[CH3:5][O:6][C:7](=[O:15])[C@H:8]([CH2:10][CH2:11][CH2:12][CH2:13][NH2:14])[NH2:9]

Participants

4

Reactant 2

HCID 111,2-Dichloroethane4×HCID 117779687-64-93×

Product 1

HCID 131716892HCID 131716892, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A 0.4%(w/w) solution of HA in water was prepared. The pH of this solution was adjusted to between 4.3 and 4.75 by addition of acid. To each 100 ml of this solution was added 0.76 g of EDC with stirring until the EDC had completely dissolved. To each 100 ml of the HA/EDC solution was added 0.20 g of lysine methyl ester (LME) with stirring until the LME had completely dissolved. The addition of HA, EDC, and LME was conducted at room temperature; once the final HA/EDC/LME solution had been formed, it was stored at 4° C. until needed.

Workup

  1. additionThe pH of this solution was adjusted to between 4.3 and 4.75 by addition of acid
  2. dissolutionhad completely dissolved
  3. dissolutionhad completely dissolved
  4. customwas conducted at room temperature

Sources & evidence

ORD record
ord-c7cec3288d4d45dda18a8db7be29ba77
Source dataset
uspto-grants-2001_01
Patent number
US06174999B1

Reaction notes

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