反应详情

A mixture of 1,1-diphenyl-1-propanol (64 g, 0.30 mol), isopropanol (300 ml) and a 5 N solution of sulphuric acid (150 ml) was heated at reflux temperature for 18 h. The reaction mixture was cooled, diluted with water (600 ml) and extracted with toluene (3×150 ml). The combined organic phases was dried (Na2SO4) and the solvent was evaporated in vacuo to give a solid residue which was triturated with iso-octane. The solid was collected by filtration to give 28.8 g (49%) of 1,1-diphenyl-1-propene.

1. temperatureat reflux temperature for 18 h
2. temperatureThe reaction mixture was cooled
3. extractionextracted with toluene (3×150 ml)
4. dry with materialThe combined organic phases was dried (Na2SO4)
5. customthe solvent was evaporated in vacuo
6. customto give a solid residue which
7. customwas triturated with iso-octane
8. filtrationThe solid was collected by filtration