Formic Acid → HCID 15480884, compound

Participants

Reaction Conditions

Reaction Steps

The intermediate 1-phenyl-2-(tritylamino)-3-[N-(2-methoxybenzyl)acetylamino]propane (8.0 g, 14.4 mmol), prepared as described in Preparation 3, supra, was dissolved in 250 ml of methylene chloride and then cooled to 0° C. under a nitrogen atmosphere. Formic acid (5.5 ml, 144.0 mmol) was then added to the reaction solution and the resulting mixture was then warmed to room temperature. The reaction mixture was then stirred for about 2.5 hours. The progress of the reaction was monitored by thin layer chromatography.

Provenance & Evidence