HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → 2-(4-Bromo-2-oxopyridin-1(2H)-yl)-3-cyclopropylpropanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | Ethyl 2-(4-bromo-2-oxopyridin-1(2H)-yl)-3-cyclopropylpropanoate | HCID 117622870 | — |
| Product | 2-(4-Bromo-2-oxopyridin-1(2H)-yl)-3-cyclopropylpropanoic acid | HCID 117622547 | — |
Reaction Steps
350 mg (1.1 mmol) of ethyl 2-(4-bromo-2-oxopyridin-1(2H)-yl)-3-cyclopropylpropanoate (racemate) were hydrolysed with lithium hydroxide according to General Method 6B. Yield: 290 mg (purity 94%, 86% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434690B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-0c9a144a9b9f4cbc8f14ce86af75f9a6 |
| Source note | uspto-grants-2016_09 |