Lithium Hydroxide → HCID 21266528, compound

Participants

Reaction Steps

To a solution of 6-acetoxy-4-m-tolyl-5,6-dihydro-1H-[5,4′]bipyridinyl-2-one (200 mg, 0.6 mmole) in THF (2 mL) and water (2 mL) at r.t. was added LiOH (51 mg, 1.2 mmole) in one portion. The reaction mixture was stirred at that temperature for 10 min before quenching the mixture with aqueous NH4Cl. The reaction was quenched with 1.45 mL of 1N HCl the resulting white precipitate was filtered, rinsed with water and dried to give the title compound as a white solid.

Provenance & Evidence