HCID 21266474, compound → HCID 21266526, compound

HRID 566730Notes

Reaction equation

Cl[C:2]1[CH:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[CH:9]=2)[C:5]([C:15]2[CH:20]=[CH:19][N:18]=[CH:17][CH:16]=2)=[CH:4][N:3]=1>C1(CCCN)C=CC=CC=1>[C:8]1([CH2:6][CH2:7][CH2:2][NH:3][C:2]2[CH:7]=[C:6]([C:8]3[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[CH:9]=3)[C:5]([C:15]3[CH:20]=[CH:19][N:18]=[CH:17][CH:16]=3)=[CH:4][N:3]=2)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

Participants

Conditions

Temperature: 160 °C

Procedure

A mixture of 2-chloro-4-(3-methylphenyl)-5-(4-pyridyl)pyridine (13 mg) and 3-phenylpropylamine (5 drops) was heated to 160° C. for 2 hr. The cooled reaction mixture was subjected to chromatographic purification (silica gel, methanol/methylene chloride) to give the title compound.

Workup

customThe cooled reaction mixture
customwas subjected to chromatographic purification (silica gel, methanol/methylene chloride)

Sources & evidence

ORD record: ord-b53c9acf405747d9bc4ea14808376c10
Source dataset: uspto-grants-2001_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06174901B1

Reaction notes

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