反应详情

305 mg (purity 77%, 0.77 mmol) of 5-chloro-4-[5-chloro-2-(difluoromethyl)phenyl]-2-methoxypyridine and 20 eq. of pyridinium chloride were reacted according to General Method 3A. After work-up, the crude product was purified by preparative HPLC (Reprosil C18, water/acetonitrile gradient). Yield: 179 mg (80% of theory)

1. customAfter work-up, the crude product was purified by preparative HPLC (Reprosil C18, water/acetonitrile gradient)