HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopropionic acid → HCID 117622834, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopropionic acid | HCID 11729 | — |
| Reactant | HCID 117605519 | HCID 117605519 | — |
| Product | HCID 117622834 | HCID 117622834 | — |
Reaction Steps
88 mg (0.31 mmol) of 4-[5-chloro-2-(difluoromethyl)phenyl]-6-oxo-1,6-dihydropyridin-3-carbonitrile and 1.5 eq. of 2-bromopropanoic acid (racemate) were reacted according to General Method 4A at 45° C. Yield: 88 mg (purity 92%, 73% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434690B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-577e3cffd4bb4999b6876b17d256dd70 |
| Source note | uspto-grants-2016_09 |