4'-(Bromomethyl)-2-cyanobiphenyl → Methyl 2-[N-(tert-Butoxycarbonyl)-N-[(2'-cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate

Participants

Role	Name	HCID	Charge
Reactant	4'-(Bromomethyl)-2-cyanobiphenyl	HCID 1501912	—
Reactant	Methyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate	HCID 9965968	—
Reactant	2-(4,4-Dibromomethylphenyl)benzonitrile	HCID 86594832	—
Product	Methyl 2-[N-(tert-Butoxycarbonyl)-N-[(2'-cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate	HCID 10874596	—

Reaction Steps

A method according to claim 1, wherein said reaction is carried out between (1) a mixture containing 2-(4-bromomethylphenyl)benzonitrile and 2-(4,4-dibromomethylphenyl)benzonitrile and (2) methyl 2-tert-butoxycarbonylamino-3-nitrobenzoate to give methyl 2-[N-t-butoxycarbonyl-N-[(2′-cyano-biphenyl-4-yl)methyl]amino]-3-nitrobenzoate.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06177587B1
Source dataset	uspto-grants-2001_01
ORD ID	ord-5cb46d7d21114f58a6ec3b0cdfbf55e5
Source note	uspto-grants-2001_01