HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclopentadiene → 8-t-Butoxycarbonyltetracyclo[4.4.0.12,5.17,10]dodeca-3-ene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclopentadiene | HCID 6492 | — |
| Reactant | Cyclopentadiene | HCID 7612 | — |
| Reactant | tert-Butyl acrylate | HCID 15458 | — |
| Reactant | Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 1,1-dimethylethyl ester | HCID 15607334 | — |
| Product | 8-t-Butoxycarbonyltetracyclo[4.4.0.12,5.17,10]dodeca-3-ene | HCID 15538966 | 40% |
Reaction Steps
The reaction was carried out in the same manner as in the Synthesis Example 1(1), except for using t-butyl acrylate, dicyclopentadiene, and 5-t-butoxycarbonylbicyclo[2.2.1]hept-2-ene at a molar ratio of 3:1(as cyclopentadiene):1 as reaction raw materials, to obtain 8-t-butoxycarbonyltetracyclo[4.4.0.12,5.17,10]dodec-3-ene of the following formula (16) at an yield of 40%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06180316B2 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-d9383f3050364303b277ccbbb6e521fc |
| Source note | uspto-grants-2001_01 |