HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 21262472, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Amino-5-methylbenzoic acid | HCID 76255 | — |
| Reactant | 2,6-Difluorobenzoyl chloride | HCID 87438 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 21262472 | HCID 21262472 | — |
Reaction Steps
2-Amino-5-methylbenzoic acid (0.5 g) and triethyl amine (10 ml) were mixed in dry toluene (20 ml). 2,6-Difluorobenzoyl chloride (1.28 g) was added dropwise under cooling and stirring. The mixture was subsequently heated to RT for 2 days. After cooling on ice the precipitate was filtered off and the filtrate evaporated to dryness.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06180625B2 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-9b445433241d43f6845691cf73c1d29e |
| Source note | uspto-grants-2001_01 |