反应详情

5-Nitroanthranilic acid (0.6 g) was dissolved in triethyl amine/toluene (1/1) (18 mL) and stirred for 10 min. 2,6-Difluorobenzoylchloride (1.3 g) was slowly added under stirring which resulted in the formation of a precipitate. The reaction was performed in an N2-atmosphere. After stirring at RT for 24 h the mixture was extracted with sat.NaHCO3 and ethyl acetate (20 mL), the organic layer was separated and evaporated.

1. stirringunder stirring which
2. customresulted in the formation of a precipitate
3. stirringAfter stirring at RT for 24 h the mixture
4. extractionwas extracted
5. customNaHCO3 and ethyl acetate (20 mL), the organic layer was separated
6. customevaporated