HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phthalide → HCID 70156297, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phthalide | HCID 6885 | — |
| Reactant | 4-Pyridinecarboxaldehyde | HCID 13389 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 70156297 | HCID 70156297 | — |
Reaction Steps
In accordance with the procedure described in Lombardino, J.O.C. Vol. 32, pp. 1988-1992 (1967), a solution of isobenzofuran-1-one (13.4 g, 0.1 mol) and 4-pyridine carboxaldehyde (10.7 g, 0.1 mol) in 100 ml dry methanol are refluxed for 2 hours. The solvent is evaporated, and the product (3-(4-pyridylmethylene)isobenzofuran-1-one is used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06180629B2 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-3620654cd23d420ab7f596ae0d533537 |
| Source note | uspto-grants-2001_01 |