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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 567726Generated: October 30, 2026

2-Fluorophenyl isocyanate → HCID 15429051, compound

https://huagongshe.com/reaction/567726

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluorophenyl isocyanateHCID 85588—
ReactantHCID 178487267HCID 178487267—
SolventTetrahydrofuranHCID 8028—
ProductHCID 15429051HCID 15429051—

Reaction Steps

1.8 g (0.013 mol) of 2-fluorophenyl isocyanate are added to a solution of 3.0 g (0.01 mol) of 5-methoxy-1-(3-nitrobenzyl)-1H-indazol-3-ol in 100 ml of tetrahydrofuran and the mixture is heated under reflux for 4 hours. It is then concentrated to 20 ml, and the precipitate deposited is filtered off with suction and recrystallized from ethyl acetate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06180637B2
Source datasetuspto-grants-2001_01
ORD IDord-7c250f40809c47f2b7e28c45e6226319
Source noteuspto-grants-2001_01