HCID 21262653, compound → HCID 20639598, compound

Participants

Reaction Steps

Analogously to the method described in stage 19.4, boiling 20.0 g (700 mmol) of 4-chloro-6-(3-nitrophenyl)-7H-pyrrolo[2,3-d]pyrimidine (prepared analogously to stages 19.1 to 19.3) with 23.1 ml (168 mmol) of (R)-phenylethylamine in 23.1 ml of n-butanol gives (R)-6-(3-nitrophenyl)-4-[(1-phenylethyl)amino]-7H-pyrrolo-[2,3-d]pyrimidine as rust-brown crystals of m.p.>250° C.; MS: M+=359.

Provenance & Evidence