HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 117622865, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 117622961 | HCID 117622961 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 117622865 | HCID 117622865 | — |
Reaction Steps
65.0 mg (142 μmol) of tert-butyl 2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-4,4,4-trifluorobutanoate (racemate) in 1.6 ml of dichloromethane and 411 μl (5.34 mmol) of TFA were reacted according to General Method 6A. Yield: 53 mg (81% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434690B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-615559ab84ff4a32a92fee6f3905f249 |
| Source note | uspto-grants-2016_09 |