2-Ethylphenyl isocyanate → N-(2-hydroxy-4-nitrophenyl)-N'-(2-ethylphenyl)urea

HRID 567986Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 567986
[OH:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1[NH2:4].[CH2:12]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[N:20]=[C:21]=[O:22])[CH3:13]>>[OH:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1[NH:4][C:21]([NH:20][C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=1[CH2:12][CH3:13])=[O:22]

Komponenten

3

Edukt 2

HCID 5834862-Ethylphenyl isocyanateHCID 49847212-Amino-5-Nitrophenol

Produkt 1

HCID 21184795N-(2-hydroxy-4-nitrophenyl)-N'-(2-ethylphenyl)ureaAusbeute 45,1 %

Versuchsvorschrift

N-(2-Hydroxy-4-nitrophenyl)-N′-(2-ethylphenyl)urea was prepared from 2-hydroxy 4-nitro aniline (500 mg, 3.24 mmol) and 2-ethylphenylisocyanate (3.24 mmol) according to the procedure in General Method B. The product was purified by dilution with methylene chloride and precipitation with hexanes. Filtering afforded the title compound(0.44 g, 43%). EI-MS m/z 302(M+H)+.

Aufarbeitung

  1. customThe product was purified by dilution with methylene chloride and precipitation with hexanes
  2. filtrationFiltering

Quellen und Nachweise

ORD-Eintrag
ord-cb9432501810406d982d44fe59027dfd
Quelldatensatz
uspto-grants-2001_01
Patentnummer
US06180675B2

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