HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromophenyl isocyanate → N-(2-hydroxy 3,4-difluorophenyl) N'-(2-bromophenyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromophenyl isocyanate | HCID 137097 | — |
| Reactant | 6-Amino-2,3-difluorophenol | HCID 2778441 | — |
| Product | N-(2-hydroxy 3,4-difluorophenyl) N'-(2-bromophenyl)urea | HCID 22011339 | — |
Reaction Steps
The urea was prepared from 2-hydroxy 3,4-difluoro aniline(0.290 g, 2 mmol) and 2-bromophenylisocyanate(0.4 g) by general Method B. It was purified by dilution with methylene chloride and precipitation with hexane(0.254 g, 37%). EI-MS m/z 343(M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06180675B2 |
| Source dataset | uspto-grants-2001_01 |
| ORD ID | ord-b6e22af946f446339b0eccb553ad24ff |
| Source note | uspto-grants-2001_01 |