反应详情

270 mg (0.59 mmol) of tert-butyl 2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-4-fluoropentanoate (mixture of racemic diastereomers) were hydrolysed with TFA according to General Method 6A. Yield: 222 mg (purity 85%, 84% of theory)