O-Phenylenediamine → 2-(Benzylsulfonylamino)aniline

HRID 568023Notes

Reaction equation

HRID 568023 reaction equation
[CH2:1]([S:8](Cl)(=[O:10])=[O:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:12]1([NH2:19])[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[NH2:18]>>[CH2:1]([S:8]([NH:18][C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=1[NH2:19])(=[O:10])=[O:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 7243O-PhenylenediamineHCID 74740Phenylmethanesulfonyl chloride

Product 1

HCID 167784432-(Benzylsulfonylamino)aniline

Procedure

The sulfonamide was synthesized from benzylsulfonyl chloride(0.01 mol) and o-phenylene diamine(0.01 mol) by general Method C. It was purified by recrystallization from EtOH(0.87g, 33%). EI-MS m/z 263(M+H)+.

Workup

  1. customIt was purified by recrystallization from EtOH(0.87g, 33%)

Sources & evidence

ORD record
ord-84e63cb069224b47bd25fa740552c59a
Source dataset
uspto-grants-2001_01
Patent number
US06180675B2

Reaction notes

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