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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 568212Generated: October 31, 2026

Dimethylformamide → HCID 70219254, compound

https://huagongshe.com/reaction/568212

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
Reactant4-Methylbenzoyl ChlorideHCID 13405—
Reactant4-Amino-m-cresolHCID 17819—
SolventTriethylamineHCID 8471—
ProductHCID 70219254HCID 7021925412%

Reaction Steps

4-Methylbenzoyl chloride was added to a DMF solution of a mixture of 4-amino-3-methylphenol and triethylamine, and stirred at room temperature for 30 minutes. The relative amount of each compound used, and the purification of the product. is described in Production Example 4. Thus was obtained the intended product, 4-hydroxy-2-methylphenyl-4-methylbenzamide (yield: 12%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06180844B2
Source datasetuspto-grants-2001_01
ORD IDord-6313b33ec239490388b1ad5064ffb9a9
Source noteuspto-grants-2001_01