HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 131736945, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 131736944 | HCID 131736944 | — |
| Product | HCID 131736945 | HCID 131736945 | — |
Reaction Steps
479 mg (797 μmol) of tert-butyl 3-(4-{[tert-butyl(dimethyl)silyl]oxy}cyclohexyl)-2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]propanoate (mixture of two racemic diastereomers) were reacted with 4 ml of aqueous lithium hydroxide solution (1N) according to General Method 6B, giving the title compound. Yield: 400 mg (80% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434690B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-07f9b26192f142d989f0f3e523c2a3a4 |
| Source note | uspto-grants-2016_09 |