Hydrochloric Acid → HCID 19867082, compound

HRID 568369Notes

Reaction equation

HRID 568369 reaction equation
[NH2:1][C:2]1[C:7]([C:8]([F:11])([F:10])[F:9])=[CH:6][C:5]([N:12]2[CH:16]=[N:15][N:14]=[CH:13]2)=[CH:4][C:3]=1/[CH:17]=[CH:18]/[C:19]([O:21]CC)=O.Cl>>[F:9][C:8]([F:11])([F:10])[C:7]1[CH:6]=[C:5]([N:12]2[CH:16]=[N:15][N:14]=[CH:13]2)[CH:4]=[C:3]2[C:2]=1[NH:1][C:19](=[O:21])[CH:18]=[CH:17]2

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 19867091HCID 19867091, compound

Product 1

HCID 19867082HCID 19867082, compound

Procedure

The following compound, m.p.>320°, was prepared similarly to the previous Example, starting from trans-ethyl 3-(2-amino-3-trifluoromethyl-5-[1,2,4-triazol-4-yl]phenyl)prop-2-enoate and 5M HCl. ##STR62##

Sources & evidence

ORD record
ord-e76f97e30b454aa0ab5b8b41ac9e557c
Source dataset
uspto-grants-1988_03
Patent number
US04728653

Reaction notes

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