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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 568397Generated: October 29, 2026

N-methyl-2-pyrrolidone → 4-(4-Amino-3-cyano-5-trifluoromethylphenyl)-1,2,4-triazole

https://huagongshe.com/reaction/568397

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methyl-2-pyrrolidoneHCID 13387—
Reactant4-(4-Amino-3-bromo-5-trifluoromethylphenyl)-1,2,4-triazoleHCID 19867072—
Product4-(4-Amino-3-cyano-5-trifluoromethylphenyl)-1,2,4-triazoleHCID 19867073—

Reaction Steps

The following compound, m.p. 283°, was similarly prepared to the previous Preparation using 4-(4-amino-3-bromo-5-trifluoromethylphenyl)-1,2,4-triazole, cuprous cyanide and 1-methyl-2-pyrrolidone as the starting materials: ##STR148##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04728653
Source datasetuspto-grants-1988_03
ORD IDord-2e4b9094d47b4ff6a968487510e3b2d5
Source noteuspto-grants-1988_03