Piperazine → HCID 20150164, compound

HRID 568423Notes

Reaction equation

Cl[C:2]1[N:3]=[C:4]([N:19]2[CH2:24][CH2:23][S:22](=[O:25])[CH2:21][CH2:20]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:6]=2[N:7]=1.[NH:26]1[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]1>>[O:25]=[S:22]1[CH2:23][CH2:24][N:19]([C:4]2[C:5]3[N:11]=[CH:10][N:9]=[C:8]([S:12][C:13]4[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=4)[C:6]=3[N:7]=[C:2]([N:26]3[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]3)[N:3]=2)[CH2:20][CH2:21]1

Participants

Reactant 2

HCID 4837Piperazine

HCID 13043380HCID 13043380, compound

Product 1

HCID 20150164HCID 20150164, compound

Procedure

This compound was prepared analogous to Example 2 from 2-chloro-4-(1-oxido-thiomorpholino)-8-phenylthio-pyrimido-[5,4-d]-pyrimidine (m.p.: 253°-255° C.) and piperazine.

Sources & evidence

ORD record: ord-beccb55f282741c99c46bb0cbfbfa85a
Source dataset: uspto-grants-1988_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04728646

Reaction notes

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