Piperazine → HCID 20150233, compound

HRID 568436Notes

Reaction equation

HRID 568436 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:20]2[CH2:25][CH2:24][O:23][CH2:22][CH2:21]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][C:13]3[CH:18]=[CH:17][C:16]([F:19])=[CH:15][CH:14]=3)[C:6]=2[N:7]=1.[NH:26]1[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]1>>[F:19][C:16]1[CH:17]=[CH:18][C:13]([S:12][C:8]2[C:6]3[N:7]=[C:2]([N:26]4[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]4)[N:3]=[C:4]([N:20]4[CH2:25][CH2:24][O:23][CH2:22][CH2:21]4)[C:5]=3[N:11]=[CH:10][N:9]=2)=[CH:14][CH:15]=1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 20150209HCID 20150209, compound

Product 1

HCID 20150233HCID 20150233, compound

Procedure

This compound was prepared analogous to Example 1 from 2-chloro-8-(4-fluorophenyl-thio)-4-morpholino-pyrimido-[5,4-d]-pyrimidine (m.p.: 213°-215° C.) and piperazine.

Sources & evidence

ORD record
ord-22d4209b200442f6b0b9ad9caa392417
Source dataset
uspto-grants-1988_03
Patent number
US04728646

Reaction notes

Loading…