Piperazine → HCID 20150252, compound

HRID 568444Notes

Reaction equation

HRID 568444 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:21]2[CH2:26][CH2:25][S:24](=[O:27])[CH2:23][CH2:22]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][CH2:13][C:14]3[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=3)[C:6]=2[N:7]=1.[NH:28]1[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]1>>[Cl:20][C:17]1[CH:16]=[CH:15][C:14]([CH2:13][S:12][C:8]2[C:6]3[N:7]=[C:2]([N:28]4[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]4)[N:3]=[C:4]([N:21]4[CH2:26][CH2:25][S:24](=[O:27])[CH2:23][CH2:22]4)[C:5]=3[N:11]=[CH:10][N:9]=2)=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 13043576HCID 13043576, compound

Product 1

HCID 20150252HCID 20150252, compound

Procedure

This compound was prepared analogous to Example 1 from 2-chloro-8-(4-chlorobenzyl-thio)-4-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine (m.p.: 232°-234° C.) and piperazine.

Sources & evidence

ORD record
ord-22ac9ad06c6a41f2bca9f4158c6a9c7f
Source dataset
uspto-grants-1988_03
Patent number
US04728646

Reaction notes

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