Piperazine → HCID 20150182, compound

HRID 568450Notes

Reaction equation

HRID 568450 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:23]2[CH2:28][CH2:27][S:26](=[O:29])[CH2:25][CH2:24]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][CH:13]([CH3:22])[C:14]3[CH:19]=[CH:18][C:17]([S:20][CH3:21])=[CH:16][CH:15]=3)[C:6]=2[N:7]=1.[NH:30]1[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]1>>[CH3:22][CH:13]([S:12][C:8]1[C:6]2[N:7]=[C:2]([N:30]3[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]3)[N:3]=[C:4]([N:23]3[CH2:28][CH2:27][S:26](=[O:29])[CH2:25][CH2:24]3)[C:5]=2[N:11]=[CH:10][N:9]=1)[C:14]1[CH:19]=[CH:18][C:17]([S:20][CH3:21])=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 13043435HCID 13043435, compound

Product 1

HCID 20150182HCID 20150182, compound

Procedure

This compound was prepared analogous to Example 1 from 2-chloro-8-(α-methyl-4-methylthiobenzyl-thio)-4-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine (m.p.: 200°-202° C.) and piperazine.

Sources & evidence

ORD record
ord-06b529345cf64650a67867cba12be546
Source dataset
uspto-grants-1988_03
Patent number
US04728646

Reaction notes

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