Piperazine → HCID 12817055, compound

HRID 568463Notes

Reaction equation

HRID 568463 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:16]2[CH2:21][CH2:20][S:19](=[O:22])[CH2:18][CH2:17]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([NH:12][CH2:13][CH2:14][CH3:15])[C:6]=2[N:7]=1.[NH:23]1[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]1>>[O:22]=[S:19]1[CH2:20][CH2:21][N:16]([C:4]2[C:5]3[N:11]=[CH:10][N:9]=[C:8]([NH:12][CH2:13][CH2:14][CH3:15])[C:6]=3[N:7]=[C:2]([N:23]3[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]3)[N:3]=2)[CH2:17][CH2:18]1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 12817001HCID 12817001, compound

Product 1

HCID 12817055HCID 12817055, compound

Procedure

This compound was prepared analogous to Example 123 from 2-chloro-4-(1-oxido-thiomorpholino)-8-propylamino-pyrimido-[5,4-d]-pyrimidine (m.p.: 174°-176° C.) and piperazine.

Sources & evidence

ORD record
ord-5a65764875f2494b9d01085d25adee53
Source dataset
uspto-grants-1988_03
Patent number
US04728646

Reaction notes

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