Piperazine → HCID 12817105, compound

HRID 568480Notes

Reaction equation

Cl[C:2]1[N:3]=[C:4]([N:19]2[CH2:24][CH2:23][S:22](=[O:25])[CH2:21][CH2:20]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([N:12]3[CH2:17][CH2:16][S:15](=[O:18])[CH2:14][CH2:13]3)[C:6]=2[N:7]=1.[NH:26]1[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]1>>[N:26]1([C:2]2[N:3]=[C:4]([N:19]3[CH2:20][CH2:21][S:22](=[O:25])[CH2:23][CH2:24]3)[C:5]3[N:11]=[CH:10][N:9]=[C:8]([N:12]4[CH2:17][CH2:16][S:15](=[O:18])[CH2:14][CH2:13]4)[C:6]=3[N:7]=2)[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]1

Participants

Reactant 2

HCID 4837Piperazine

HCID 20150162HCID 20150162, compound

Product 1

HCID 12817105HCID 12817105, compound

Procedure

This compound was prepared analogous to Example 118 from 2-chloro-4,8-bis-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine (m.p.: 295°-297° C.) and piperazine.

Sources & evidence

ORD record: ord-eb61ef5424bd4801b1a3fe3ecaefd458
Source dataset: uspto-grants-1988_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04728646

Reaction notes

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