Sodium Acetate → HCID 178506542, compound

HRID 568488Notes

Reaction equation

HRID 568488 reaction equation
[C:1]1([C:7]2[N:8]([CH2:12][CH2:13][CH2:14][NH2:15])[CH:9]=[CH:10][N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[IH:16].CS[C:19]1[C:27]2[CH:28]=[CH:29][CH:30]=[C:25]3[C:26]=2[C:21](=[CH:22][CH:23]=[CH:24]3)[N:20]=1.C([O-])(=O)C.[Na+]>C(O)C>[IH:16].[C:1]1([C:7]2[N:8]([CH2:12][CH2:13][CH2:14][NH:15][C:19]3[C:27]4[CH:28]=[CH:29][CH:30]=[C:25]5[C:26]=4[C:21](=[CH:22][CH:23]=[CH:24]5)[N:20]=3)[CH:9]=[CH:10][N:11]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 135889112-phenyl-1H-imidazole-1-propanamineHCID 201506502-Methylthiobenz(cd)indole hydriodide

Product 1

HCID 178506542HCID 178506542, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 4.0 g of 3-(2-phenyl-1H-imidazol-1-yl)propanamine, 6.5 g of 2-(methylthio)benz[cd]indole hydroiodide, 1.8 g of sodium acetate and 250 ml of ethanol was reacted as described in Example 11. The crude product was recrystallized from a mixture of ethanol and isopropanol giving 3.8 g of the desired product, mp 153° C.-155° C.

Workup

  1. customwas reacted
  2. customThe crude product was recrystallized from a mixture of ethanol and isopropanol giving 3.8 g of the desired product, mp 153° C.-155° C.

Sources & evidence

ORD record
ord-94426a4fab0e4a74b7e098f23b6c070b
Source dataset
uspto-grants-1988_03
Patent number
US04728663

Reaction notes

Loading…