Sodium Acetate → HCID 178432904, compound

HRID 568489Notes

Reaction equation

HRID 568489 reaction equation
[CH3:1][C:2]1[N:3]([CH2:7][CH2:8][CH2:9][NH2:10])[CH:4]=[CH:5][N:6]=1.[IH:11].CS[C:14]1[C:22]2[CH:23]=[CH:24][CH:25]=[C:20]3[C:21]=2[C:16](=[CH:17][CH:18]=[CH:19]3)[N:15]=1.C([O-])(=O)C.[Na+]>C(O)C>[IH:11].[CH3:1][C:2]1[N:3]([CH2:7][CH2:8][CH2:9][NH:10][C:14]2[C:22]3[CH:23]=[CH:24][CH:25]=[C:20]4[C:21]=3[C:16](=[CH:17][CH:18]=[CH:19]4)[N:15]=2)[CH:4]=[CH:5][N:6]=1

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 31521053-(2-methyl-1H-imidazol-1-yl)propan-1-amineHCID 201506502-Methylthiobenz(cd)indole hydriodide

Product 1

HCID 178432904HCID 178432904, compoundYield 15.8%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 2.1 g of 3-(2-methyl-1H-imidazol-1-yl)propanamine, 5.0 g of 2-(methylthio)benz[cd]indole hydroiodide, 1.4 g of sodium acetate and 250 ml of ethanol was reacted as described in Example 13, giving 1.0 g of the desired product, mp 153°-155° C.

Workup

  1. customwas reacted

Sources & evidence

ORD record
ord-add3a2e67b7646968b466d125c5cf5d8
Source dataset
uspto-grants-1988_03
Patent number
US04728663

Reaction notes

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