1H-Imidazole-1-pentanamine → HCID 178478173, compound

HRID 568501Notes

Reaction equation

HRID 568501 reaction equation
[Cl:1][C:2]1[C:3]2[C:4]3[C:8](=[C:9]([Cl:11])[CH:10]=1)[N:7]=[C:6](S)[C:5]=3[CH:13]=[CH:14][CH:15]=2.[N:16]1([CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][NH2:26])[CH:20]=[CH:19][N:18]=[CH:17]1>CN(C)C=O>[Cl:1][C:2]1[C:3]2[C:4]3[C:8](=[C:9]([Cl:11])[CH:10]=1)[N:7]=[C:6]([NH:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][N:16]1[CH:20]=[CH:19][N:18]=[CH:17]1)[C:5]=3[CH:13]=[CH:14][CH:15]=2

Participants

4

Reactant 2

HCID 71384341H-Imidazole-1-pentanamineHCID 178527805HCID 178527805, compound

Product 1

HCID 178478173HCID 178478173, compoundYield 24.5%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A mixture of 5.0 g of 6,8-dichloro-benz[cd]indole-2-thiol, 3.1 g of 5-(1H-imidazol-1-yl)pentanamine, 100 ml of dry dimethylformamide and 6.3 g of mercuric acetate was reacted as described in Example 1, giving 1.8 g of the desired product, mp 191°-192.5° C.

Workup

  1. customwas reacted

Sources & evidence

ORD record
ord-92d72ce045ba4c898ed3d2ca5bf9f9bf
Source dataset
uspto-grants-1988_03
Patent number
US04728663

Reaction notes

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