化工社化工社 化学情報印刷レポート · 研究参考用
2,3-Dichloroanisole → 2,3-Dichloro-4-methoxy-4'-fluorobenzophenone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,3-Dichloroanisole | HCID 16126 | — |
| 反応物 | 4-Fluorobenzoyl chloride | HCID 67879 | — |
| 反応物 | Aluminum(III) Chloride | HCID 6451240 | — |
| 溶媒 | 1,2-Dichloroethane | HCID 11 | — |
| 生成物 | 2,3-Dichloro-4-methoxy-4'-fluorobenzophenone | HCID 20150631 | — |
反応手順
The Friedel-Crafts procedure of Example 24a is repeated with 31.55 g of p-fluorobenzoyl chloride, 32 g of 2,3-dichloroanisole and 35.22 g of AlCl3 combined in 1,2-dichloroethane and reacted. The resultant crude product is triturated with warm hexane, cooled and filtered to yield 2,3-dichloro-4-methoxy-4'-fluorobenzophenone.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04728662 |
| 出典データセット | uspto-grants-1988_03 |
| ORD ID | ord-0cdad6fa654a491e90f7ef1e1e3944e1 |
| 出典メモ | uspto-grants-1988_03 |