反应详情

To a solution of 1.8 g (0.005 mol) of bis(4-fluorophenyl)methyl(5-methylthio-1H-1,2,4-triazol-1-ylmethyl)silane in 15 mL of methylene chloride cooled to 0° C. was added 1.1 g (0.005 mol) of m-chloroperbenzoic acid (80%). The reaction temperature rose to 10°. The reaction mixture was stirred at 25° for 3 hours, then diluted with methylene chloride, washed with 7% aqueous NaHCO3 and brine, dried over Na2SO4 and evaporated to give 2.1 g of the title compound as an oil, pure except for traces of solvent and starting material: nD 1.5717; ir (neat) 3020, 1590, 1500, 1232, 1164, 1110, 1070, 825 cm-1 ; nmr (CDCl3) δ 0.7 (3H, s), 2.8 (3H, s), 4.6 (2H, ABq), 7.1 (4H, m), 7.5 (4H, m), 7.9 (1H, s).

1. customrose to 10°
2. washwashed with 7% aqueous NaHCO3 and brine
3. dry with materialdried over Na2SO4
4. customevaporated