Cyanogen Bromide → HCID 178429220, compound

Participants

Reaction Steps

3.00 g. (0.016 mole) 5,6-diamino-3,3-dimethylindolin-2-one are suspended in 100 ml. ethanol and mixed at ambient temperature with 1.82 g. (0.017 mole) cyanogen bromide and stirred for 2 hours. The solvent is removed in a vacuum and the residue is dissolved in ethanol, treated with active charcoal and the product precipitated out by the addition of acetone. The product is crystallised from acetone and a little ethanol to give 1.05 g. (22% of theory) of the title compound in the form of the hydrobromide; m.p. 300°-305° C.

Provenance & Evidence