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HRID56884

反应详情

EQUATION

反应方程式

HRID 56884 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)C(F)(F)F
HCID6422

未命名化合物

结构：COc1cn(C(CC2CC(F)(F)C2)C(=O)OC(C)(C)C)c(=O)cc1-c1cc(Cl)ccc1C#N
HCID117622712

未命名化合物

PRODUCTS

生成物

1
结构：COc1cn(C(CC2CC(F)(F)C2)C(=O)O)c(=O)cc1-c1cc(Cl)ccc1C#N
HCID117622597

未命名化合物

PROCEDURE

实验过程

184 mg (0.37 mmol) of tert-butyl 2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-3-(3,3-difluorocyclobutyl)propanoate (racemate) were hydrolysed with TFA according to General Method 6A. Yield: 200 mg (purity 88%, quant.)