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HRID5689

反应详情

EQUATION

反应方程式

HRID 5689 的结构方程式

REACTANTS

反应物

1
结构：CC(C)OC(=O)C[C@H]1C[C@@H](CC#N)OC(C)(C)O1
HCID10999646

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)OC(=O)C[C@H]1C[C@@H](CCN)OC(C)(C)O1
HCID11139823

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[O]=[Pt]=[O]
催化剂HCID345198

Platinic oxide

O2Pt

结构：CC(=O)O
溶剂HCID176

Acetic Acid

C2H4O2

PROCEDURE

实验过程

A mixture of (±)-cis-1-methylethyl 6-(cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetate, 0.55 g, in glacial acetic acid is hydrogenated with platinum dioxide at 50 pounds per square inch (PSI). Concentration, dilution with ethyl acetate and bicarbonate wash, followed by washing with brine and drying provides 250 mg of (±)-cis-1-methylethyl 6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate. MS 260.1, 244.1

WORKUP

后处理

  1. concentrationConcentration, dilution with ethyl acetate and bicarbonate
  2. washwash
  3. washby washing with brine
  4. customdrying