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HRID56902

反应详情

EQUATION

反应方程式

HRID 56902 的结构方程式

REACTANTS

反应物

2
结构：[Li+].[OH-]
HCID3939

Lithium hydroxide anhydrous

HLiO

结构：CCOC(=O)C(C(C)C)n1cc(OC)c(-c2cc(Cl)ccc2C#N)cc1=O
HCID117622794

未命名化合物

PRODUCTS

生成物

1
结构：COc1cn(C(C(=O)O)C(C)C)c(=O)cc1-c1cc(Cl)ccc1C#N
HCID117622540

未命名化合物

PROCEDURE

实验过程

3.70 g (9.52 mmol) of ethyl 2-[4-(5-chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-3-methylbutanoate (racemate) were hydrolysed with lithium hydroxide according to General Method 6B. Yield: 2.80 g (82% of theory)