m-Chloroperbenzoic acid → HCID 13315110, compound

HRID 569024Notes

Reaction equation

HRID 569024 reaction equation
[CH3:1][S:2][CH2:3][C:4]1[N:5]=[CH:6][C:7]2[NH:8][C:9]3[C:14]([C:15]=2[CH:16]=1)=[CH:13][CH:12]=[CH:11][CH:10]=3.ClC1C=CC=C(C(OO)=[O:25])C=1>C(Cl)Cl>[CH3:1][S:2]([CH2:3][C:4]1[N:5]=[CH:6][C:7]2[NH:8][C:9]3[C:14]([C:15]=2[CH:16]=1)=[CH:13][CH:12]=[CH:11][CH:10]=3)=[O:25]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 13315109HCID 13315109, compound

Product 1

HCID 13315110HCID 13315110, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

160 mg of 3-methylthiomethyl-β-carboline are stirred in 15 ml of methylene chloride with 163 mg of m-chloroperbenzoic acid for 3 hours at room temperature. After extraction with semiconcentrated sodium bicarbonate solution, the organic phase is dried, filtered and concentrated. The residue is stirred with ethyl acetate/ethanol. 76 mg of 3-methylsulfinylmethyl-β-carboline with a 175°-178° C. melting point are obtained as a residue.

Workup

  1. extractionAfter extraction with semiconcentrated sodium bicarbonate solution
  2. customthe organic phase is dried
  3. filtrationfiltered
  4. concentrationconcentrated
  5. customwith a 175°-178° C.
  6. customare obtained as a residue

Sources & evidence

ORD record
ord-9fc0bd1fc17047ff9287dde7590b8bae
Source dataset
uspto-grants-1988_03
Patent number
US04731358

Reaction notes

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