Ethanol → HCID 13315133, compound

Participants

Reaction Steps

950 mg of 6-nitro-3-methylthio-β-carboline are hydrogenated in 80 ml of tetrahydrofuran and 80ml of ethanol with 200 mg of palladium/carbon (10%) for 7.5 hours at room temperature under normal hydrogen pressure. After filtration and concentration, the residue is chromatographed on silica gel with methylene chloride/acetone=1:1 as eluant. 600 mg of 6-amino-3-methylthio-β-carboline with a 202° C. melting point are obtained.

Provenance & Evidence