Allyl bromide → HCID 20148438, compound

Participants

Reaction Steps

360 mg of 6-amino-β-carboline are heated in 20 ml of ethanol with 0.54 ml of allylbromide and 0.74 ml diazabicycloundecene for 3 hours at 70° C. After concentration to dryness and dispersing in ethyl acetate/saturated sodium chloride solution, the organic phase is separated, dried, filtered and concentrated. The residue is chromatographed on silica gel with cyclohexane/ethyl acetate=1:1 as eluant and 50 mg of 6-diallylamino-β-carboline as oil are obtained.

Provenance & Evidence