HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Ethoxycarbonyl-3-(2-nitrovinyl)indole → 3-(2-Aminoethyl)-4-ethoxycarbonyl indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Ethoxycarbonyl-3-(2-nitrovinyl)indole | HCID 54059630 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | 3-(2-Aminoethyl)-4-ethoxycarbonyl indole | HCID 20148415 | — |
Reaction Steps
0.5 g of 4-ethoxycarbonyl-3-(2-nitrovinyl)indole are heated under nitrogen for 45 minutes in the steam bath in 50 ml of formic acid with 1.5 g of 10% palladium-carbon. The palladium carbon is then filtered off, the filtrate evaporated, the evaporation residue [3-(2-aminoethyl)-4-ethoxycarbonyl indole] is then further reacted immediately.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04731358 |
| Source dataset | uspto-grants-1988_03 |
| ORD ID | ord-745681e89a314f3f872047bb78ff51a8 |
| Source note | uspto-grants-1988_03 |