Hydrogen Peroxide → HCID 20148578, compound

HRID 569061Notes

Reaction equation

HRID 569061 reaction equation
[S:1]1[C:5]2=[N:6][CH:7]=[CH:8][CH:9]=[C:4]2[CH:3]=[C:2]1[S:10]([NH2:13])(=[O:12])=[O:11].[OH:14]O>C(O)(=O)C.O>[S:10]([C:2]1[S:1][C:5]2=[N+:6]([O-:14])[CH:7]=[CH:8][CH:9]=[C:4]2[CH:3]=1)(=[O:12])(=[O:11])[NH2:13]

Participants

5

Reactant 2

HCID 784Hydrogen PeroxideHCID 20148561115063-67-7

Product 1

HCID 20148578HCID 20148578, compoundYield 76%

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 962WaterSolvent

Conditions

Temperature
55 °C

Procedure

A mixture of thieno[2,3-b]pyridine-2 Sulfonamide (0.43 g, 2 mmol) and 30% hydrogen peroxide (1.0 ml) in acetic acid (5.0 ml) was stirred at 55° C. for 24 hours. The reaction mixture was diluted with water, chilled and the resulting solid was collected and dried; 0.35 g (76% yield); m.p. 278°-279° C.

Workup

  1. temperaturechilled
  2. customthe resulting solid was collected
  3. customdried

Sources & evidence

ORD record
ord-26f4ad8c2735448da59266bf2cd22490
Source dataset
uspto-grants-1988_03
Patent number
US04731368

Reaction notes

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