Hydrochloric Acid → HCID 13784605, compound

Participants

Reaction Steps

In 25 ml of ethanol was dissolved 4.3 g of 4-(3-formyl-2-hydroxyphenyloxy)butyric acid and 1.35 g of malononitrile, to which 3 ml of an aqueous solution containing 0.12 g of potassium fluoride was added at 40° C. and the mixture was vigorously stirred for 2 minutes. Then 5 ml of concentrated hydrochloric acid was added and the mixture was stirred for 3 minutes, followed by ice-cooling. A precipitate was filtered and recrystallized to give a desired compound.

Provenance & Evidence